(S)-2-(1-((9H-Purin-6-yl)amino)propyl)-3-(3-fluorophenyl)-4H-chromen-4-one

• Catalog: OFC1639417530
• CAS: 1639417-53-0
• Category: Fluorinated Ketones
• Synonyms: Tenalisib
• Purity: >95%
• MDL Number: MFCD28502205

• Molecular Formula: C23H18FN5O2
• Molecular Weight: 415.42
• Molar Refractivity: 116.53

• Bioavailability Score: 0.55
• Egan: 0.0
• Ghose: None
• Lipinski: 0.0
• Muegge: 0.0
• Veber: 0.0
• Consensus LogP: 3.83
• MLogP: 2.4
• SILICOS-IT: 4.96
• WLogP: 4.73
• XLogP3: 4.21
• iLogP: 2.87
• BBB Permeant: No
• CYP1A2 Inhibitor: No
• CYP2C19 Inhibitor: No
• CYP2C9 Inhibitor: Yes
• CYP2D6 Inhibitor: Yes
• CYP3A4 Inhibitor: Yes
• GI Absorption: High
• LogKp: -5.84 cm/s
• P-gp Substrate: Yes
• Fraction Csp3: 0.13

• GHS Pictogram: GHS07
• Hazard Statements: H302-H315-H319-H335
• Precautionary Statements: P261-P305+P351+P338