N-(4-(4-Methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide

• Catalog: OFC1801787563
• CAS: 1801787-56-3
• Category: Fluorinated Amides
• Synonyms: OICR-9429
• Purity: 97%
• MDL Number: MFCD28411621

• Molecular Formula: C29H32F3N5O3
• Molecular Weight: 555.59
• Molar Refractivity: 157.95

• Bioavailability Score: 0.55
• Egan: 0.0
• Ghose: None
• Lipinski: 1.0
• Muegge: 0.0
• Veber: 0.0
• Consensus LogP: 3.4
• MLogP: 2.58
• SILICOS-IT: 4.64
• WLogP: 3.56
• XLogP3: 2.22
• iLogP: 4.0
• BBB Permeant: No
• CYP1A2 Inhibitor: No
• CYP2C19 Inhibitor: Yes
• CYP2C9 Inhibitor: Yes
• CYP2D6 Inhibitor: Yes
• CYP3A4 Inhibitor: No
• GI Absorption: High
• LogKp: -8.11 cm/s
• P-gp Substrate: Yes
• Fraction Csp3: 0.38

• GHS Pictogram: GHS07
• Hazard Statements: H315
• Precautionary Statements: P280