5-(4-Fluorophenyl)-1-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide

• Catalog: OFC125995031
• CAS: 125995-03-1
• Category: Fluorinated Amides
• Synonyms: Atorvastatin lactone
• Purity: 96%
• MDL Number: MFCD00899262

• Molecular Formula: C33H33FN2O4
• Molecular Weight: 540.62
• Molar Refractivity: 154.49

• Bioavailability Score: 0.17
• Egan: 1.0
• Ghose: None
• Lipinski: 2.0
• Muegge: 1.0
• Veber: 0.0
• Consensus LogP: 5.51
• MLogP: 4.28
• SILICOS-IT: 6.41
• WLogP: 7.02
• XLogP3: 5.74
• iLogP: 4.11
• BBB Permeant: No
• CYP1A2 Inhibitor: No
• CYP2C19 Inhibitor: Yes
• CYP2C9 Inhibitor: Yes
• CYP2D6 Inhibitor: Yes
• CYP3A4 Inhibitor: Yes
• GI Absorption: Low
• LogKp: -5.52 cm/s
• P-gp Substrate: Yes
• Fraction Csp3: 0.27

• GHS Pictogram: GHS07
• Hazard Statements: H315-H319-H335
• Precautionary Statements: P261-P305+P351+P338