1-(2,4-Difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

• Catalog: OFC105784610
• CAS: 105784-61-0
• Category: Fluorinated Carboxylic Acid
• Synonyms: Temafloxacin hydrochloride
• Purity: 97%
• MDL Number: MFCD00903771

• Molecular Formula: C21H19ClF3N3O3
• Molecular Weight: 453.84
• Molar Refractivity: 119.51

• Bioavailability Score: 0.55
• Egan: 0.0
• Ghose: None
• Lipinski: 0.0
• Muegge: 0.0
• Veber: 0.0
• Consensus LogP: 2.29
• MLogP: 3.2
• SILICOS-IT: 3.43
• WLogP: 4.21
• XLogP3: 0.6
• iLogP: 0.0
• BBB Permeant: Yes
• CYP1A2 Inhibitor: No
• CYP2C19 Inhibitor: No
• CYP2C9 Inhibitor: No
• CYP2D6 Inhibitor: No
• CYP3A4 Inhibitor: No
• GI Absorption: High
• LogKp: -8.64 cm/s
• P-gp Substrate: Yes
• Fraction Csp3: 0.24

• GHS Pictogram: GHS07
• Hazard Statements: H302-H315-H319-H332-H335
• Precautionary Statements: P261-P280-P305+P351+P338