Ezetimibe

Description: Ezetimibe lowers plasma cholesterol levels.

• Catalog: OFC163222331
• CAS: 163222-33-1
• Category: Fluorinated APIs
• Synonyms: Ezetrol
• Purity: 97%

• IUPAC Name: (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
• InChI: InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1
• InChI Key: OLNTVTPDXPETLC-XPWALMASSA-N
• Isomeric SMILES: C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)O
• EC Number: 682-606-0

• Molecular Formula: C24H21F2NO3
• Molecular Weight: 409.4
• Appearance: Off-white powder

• XLogP3-AA: 4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 409.14894986 g/mol
• Monoisotopic Mass: 409.14894986 g/mol
• Topological Polar Surface Area: 60.8Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 567