Recombinant Human Collagen Type II α1 / COL2A1

Recombinant Human Collagen Type II α1 / COL2A1

Recombinant Human Collagen Type II α1 / COL2A1
Recombinant Human Collagen Type II a1 / COL2A1

General Information

  • Product Name: Recombinant Human Collagen Type II α1 / COL2A1
  • Catalog: RHC-II-001
  • Purity: ≥ 92% as determined by SDS-PAGE
  • Species: Human

Description

Human collagen type II is the major collagen of the extracellular matrix of mature articular cartilage. Together with the other cartilage collagens, the highly cross-linked fibrils of triple helical type II collagen molecules form a fibrillar network that confers tensile strength to articular surfaces. In addition to its structural function, COL2A1 is also an important extracellular signaling molecule, which can regulate the proliferation, metabolism and differentiation of chondrocytes similar to soluble signals. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.

The technical parameters of recombinant human collagen type II α1 / COL2A1 we supplied are as follows.

ItemsSpecification
Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
Molecular Weight29.8 kDa (calculated molecular mass)
37 kDa (In SDS-PAGE under reducing conditions)
Expressed HostExpressed Host
AA SequenceAsp1242~Leu1487
Intended UseFor research use only
pH7.4
Predicted N TerminalHis
SynonymsANFH Protein, Human; AOM Protein, Human; SEDC Protein, Human; STL1 Protein, Human
FormLyophilized powder
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
(For any questions or special requests, please contact us.)
StorageStore at -20℃ to -80℃ for 12 months
ShippingRecombinant proteins provided as lyophilized powder are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid.

Alfa Chemistry is a professional synthetic biology company that manufactures recombinant collagen and other high-value proteins at scale. For high quality products and more information, please feel free to contact us.

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Please kindly note that our products and services are for research use only.