Found in cartilage, bones, blood vessels, skin and other connective tissues, collagens are the most abundant proteins by weight in the human body (figure 1) [1]. Collagen is an important building block for the skin. It makes up to 30% of the protein in our body and 70% of the protein within our skin.
Fig. 1 Collagens in human
Collagen is a fibrous protein that conforms to the connective tissues of the body, essentially skin, joints, and bones. Over time, the fibers are damaged and as one of the many effects, it gives the skin an unwelcome wrinkled effect. After precise research, it has been shown that damaged fibers can be replaced by new ones when subjects ingest hydrolyzed protein. This leads to collagen production stimulation that helps restore and improve the appearance of the tissue. As a result, the cosmetic industry has made great efforts to incorporate collagen into several available products.
Uses of Recombinant Human Collagen
In cosmetic field, as with excellent moisturizing effect, anti-aging and firming, recombinant human collagen can be carried out for the skin repair of dermatitis, acne, sensitive skin and other skin problems. Currently, recombinant human collagens have been investigated in many cosmetic applications, including:
Cosmetic Benefits of Recombinant Human Collagen
The most relevant collagen sources of collagens for cosmetic industry include the natural sources and synthetic sources. Recombinant human collagen, as a product prepared by the synthetic method, provides a reliable, predictable and chemically defined source in cosmetic industry. Recombinant human collagen shows many benefits in cosmetics, such as:
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Made from non-animal sources, it is highly consistent with human collagen and is non-allergenic, with no risk of skin irritation or any other reactions caused by animal collagen.
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With excellent water solubility, it can be dissolved in water instantly.
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With good transdermal absorption, it can arrive at the dermal fibroblasts quickly.
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With excellent bioactivity and biocompatibility, it repairs damaged collagen fiber networks and promotes cell growth to shape healthy and resilient skin.
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It is excellent and efficient at anti-wrinkle and anti-aging, as well as being an excellent UV film-forming agent.
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It is excellent at moisturizing lightening and repairing skin.
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It is pH-neutral and compatible with many cosmetic products; thus, it will not affect the acid-base balance.
Alfa Chemistry is a professional synthetic biology company that manufactures recombinant human collagen and other high-value proteins at scale. For high quality products and more information, please feel free to contact us.
Reference
- Brian Bell. UCI researchers quantify, characterize and identify functions of collagen, its subtypes. Nature Reviews Materials, 2020.
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