Recombinant Human Pro-Collagen Type I α1 / COL1A1
General Information
- Product Name: Recombinant Human Pro-Collagen Type I α1 / COL1A1
- Catalog: RHC-I-002
- Purity: ≥ 95% within Alpha
- Applications: Suitable for electrospinning and applications where highly soluble collagen is needed.
Description
Collagen type I is the most abundant form of collagen in human tissues and is composed of two identical α-1 type I chains and an α-2 type I chain organized in a triple helical structure. Specifically, collagen type I alpha 1 chain (COL1A1), an extracellular matrix protein mapped to 17q21.33, is an important member of the collagen family.
Our recombinant human pro-collagen type I α1 / COL1A1 is available as full-chain or single chain molecules. Its synthesis and assembly require a multitude of genes and post-translational modifications which gives a more native human structure. It is highly soluble in physiological buffers; thus, no aggressive solvents are required for its processing in medical devices.
The technical parameters of recombinant human pro-collagen type I α1 / COL1A1 we supplied are as follows.
| Items | Specification |
| Appearance (Form) | Liquid |
| Appearance (Color) | Colorless to Slight Yellow |
| Concentration as tested | 3.0 mg/mL ± 0.2 |
| Electrophoretic Pattern | ≥ 95% Within Alpha
≤ 5% Faster Than Alpha |
| pH | 7.0 ± 0.4 |
| SDS PAGE Gel | Tris Acetate |
| SDS PAGE Stain | Coomassie |
| Endotoxin Level (LAL) | <0.5 EU/mL |
| Sterility | No Growth, 0.2μm Filtered |
| Solubility (Solvent) | Water, PBS, Buffered Media, Acetic Acid |
| Solubility (Turbidity) | Clear |
| Storage Temperature | 2 – 8 °C |
| Species | Human |
| Expiry | 18 Months at 4°C |
* Alfa Chemistry also provides recombinant human pro-collagen type I α1 / COL1A1 in lyophilized powder.
Alfa Chemistry is a professional synthetic biology company that manufactures recombinant collagen and other high-value proteins at scale. Process of our recombinant collagens avoids the use of harsh solvents, enzymes, and other manufacturing steps to ensure protein structure is retained. For high quality products and more information, please feel free to contact us.
Possibilities are unlimited with Alfa Chemistry. Let's discuss your idea.
Please kindly note that our products and services are for research use only.
