3-Aminopropylsilanetriol

• CAS: 58160-99-9
• Catalog Number: ACM58160999-3
• Category: Main Products
• Molecular Weight: 137.21
• Molecular Formula: C3H11NO3Si
• Boiling Point: 297.659 °C (760 mmHg)
• Flash Point: 133.82 °C
• Density: 1.248 g/mL
• Appearance: Liquid

Case Study

Application of 3-Aminopropylsilanetriol in the Functionalization of Strontium-Containing Mesoporous Bioactive Glasses

Pontremoli C, et al. Journal of Colloid and Interface Science, 2020, 563, 92-103.

Functionalization of Strontium-Containing Mesoporous Bioactive Glasses (Sr-MBGs) with 3-aminopropylsilanetriol (APST) and carboxyethylsilanetriol sodium salt (CES) imparted zwitterionic surface groups that reduced biomolecule adsorption and bacterial adhesion. The functionalized Sr-MBGs retained their bioactivity and continued to release Sr²⁺ ions, crucial for inducing mineralization.
Experimental Procedure: Zwitterionic Sr-MBGs
Initially, 0.5 g of dried Sr-MBG powder was outgassed overnight under vacuum and then dispersed in 100 mL of absolute ethanol. The quantities of 3-aminopropylsilanetriol (APST) (22~25% in water, Alfa Chemistry) and carboxyethylsilanetriol sodium salt (CES) required for the reaction were determined using the Zhuravlev number, which estimates the density of silanol groups (4.9 SiOH/nm²) on the surface of mesoporous materials. This method allowed for the precise calculation of precursor amounts, based on the specific surface area and available hydroxyl groups on the Sr-MBGs.
Several adjustments were made throughout the process to optimize the grafting efficiency. ζ-potential measurements were utilized to assess the changes in surface charge and guide modifications needed to achieve the desired zwitterionic character.
An equimolar mixture of APST and CES (0.3 mmol each) was added to the ethanol suspension, followed by 24 hours of refluxing at 80°C under nitrogen, with constant stirring (200 rpm). After the reaction, the functionalized Sr-MBGs were filtered, washed three times with absolute ethanol, and dried overnight at 70°C.

Custom Reviews

August 17, 2023

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Commonly used synthetic raw materials
In the experiment, the structure of 3-aminopropylsilanetriol provides a stable intermediate for the synthesis of the target product.

Custom Q&A

What is the Molecular formula of 3-Aminopropylsilanetriol?

C3H11NO3Si

What is the Molecular weight of 3-Aminopropylsilanetriol?

137.21

What is the EC number of 3-Aminopropylsilanetriol?

261-145-5

What is the InChIKey of 3-Aminopropylsilanetriol?

JTXUAHIMULPXKY-UHFFFAOYSA-N

What is the SMILES of 3-Aminopropylsilanetriol?

C(CN)C[Si](O)(O)O

What is the Form of 3-Aminopropylsilanetriol?

Liquid

What is the Chemical reactivity of 3-Aminopropylsilanetriol?

3-Aminopropylsilanetriol contains an amino group (NH2) and a hydroxyl group (OH), both of which can undergo various chemical reactions. It readily reacts with siliceous surfaces, such as glass, silicon, or metal oxide surfaces, through silanol condensation reactions. These reactions enable APS to form stable, covalent bonds with the substrate, providing functionalization and improved adhesion.

What is the Solubility of 3-Aminopropylsilanetriol?

3-Aminopropylsilanetriol is soluble in water, alcohol, and other polar solvents. It can form stable solutions or dispersions in these solvents.

What is the Application of 3-Aminopropylsilanetriol?

3-Aminopropylsilanetriol can be used as a coating agent to modify the surface properties of materials, such as glass, metals, or polymers.

What is the Density of 3-Aminopropylsilanetriol?

1.247 g/cm³