Acetamiprid

CAS

135410-20-7

Catalog Number

ACM135410207-1

Category

Main Products

Molecular Weight

222.68

Molecular Formula

C10H11ClN4

MSDS COA Spec Sheet

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Specification

Synonyms

N-[(6-chloropyridin-3-yl)methyl]-N-cyano-N-methylethanimidamide; (1E)-N-[(6-chloro-3-pyridinyl)methyl]-N'-cyano-N-methylethanimidamide; (E)-N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1-methylacetamidine; (E)-N-(6-Chloro-3-pyridylmethyl)-N-cyano-N-methylacetamidine; acetamiprid; Acetamiprid; (1E)-N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide; (E)-N-((6-Chloropyridin-3-yl)methyl)-N-cyano-N-methylacetimidamide;

IUPAC Name

N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide

Canonical SMILES

CC(=NC#N)N(C)CC1=CN=C(C=C1)Cl

InChI Key

WCXDHFDTOYPNIE-UHFFFAOYSA-N

Boiling Point

352.4ºC at 760 mmHg

Melting Point

101-103ºC

Flash Point

166.9ºC

Density

1.17

Appearance

powder form

Application

Acetamiprid is an organic compound with the chemical formula C₁₀H₁₁ClN₄. It is an odorless neonicotinoid insecticide produced under the trade names Assail, and Chipco by Aventis CropSciences.

Storage

Room temperature

EC Number

603-921-1

Exact Mass

222.06700

Hazard Statements

T: Toxic;

Packing Group

III

Safety Description

S45

Sublethal Effects of Acetamiprid on DNA Damage and Locomotion in Drosophila Species

Genotoxic effects of sub-lethal doses of nicotine and acetamiprid in neuroblasts of Drosophila melanogaster and Drosophila suzukii

Lewandowska-Wosik A, et al. Ecotoxicology and Environmental Safety, 2024, 280, 116585.

This study focuses on the neurotoxic and genotoxic effects of sublethal doses of acetamiprid on Drosophila melanogaster and Drosophila suzukii over multiple generations, highlighting DNA damage and impaired locomotion as key concerns.
Methodology: Multigenerational cultures of D. melanogaster and D. suzukii were raised on media containing sublethal concentrations of acetamiprid and nicotine. Neurotoxic and genotoxic effects were assessed through climbing tests to measure locomotion and genetic analyses to detect DNA damage in neuroblasts. The persistence of these effects across generations was also examined.
Results: Both species exhibited significant DNA damage in neuroblasts at sublethal acetamiprid concentrations. D. suzukii was more sensitive to the insecticide, showing greater neurotoxic effects compared to D. melanogaster. Behavioral tests indicated reduced mobility in both species, which persisted across generations. This chronic exposure also led to resistance to neonicotinoids over time, potentially compromising long-term pest control efficacy.
Conclusion: Even at sublethal concentrations, acetamiprid caused DNA damage and impaired locomotion in Drosophila species, with D. suzukii exhibiting heightened sensitivity. These findings underscore the need for re-evaluating the long-term ecological impact of neonicotinoids, particularly concerning their genotoxicity and the risk of pest resistance under chronic low-dose exposure.

August 19, 2023

New insecticide
Acetamiprid has contact toxicity, stomach toxicity and strong osmotic effect, and is a new type of insecticide in our research.

What is the molecular formula of Acetamiprid?

The molecular formula of Acetamiprid is C10H11ClN4.

What are some synonyms of Acetamiprid?

Some synonyms of Acetamiprid are Intruder, Mospilan, Assail, Piorun, Stonkat, Prize, Acetamiprid [ISO], and (E)-N-((6-Chloropyridin-3-yl)methyl)-N'-cyano-N-methylacetimidamide.

What is the Chemical Safety of Acetamiprid?

Acetamiprid is classified as an Acute Toxic, Irritant, Health Hazard, and Environmental Hazard.

What are the CAS numbers of Acetamiprid?

The CAS numbers of Acetamiprid are 135410-20-7 and 160430-64-8.

What is the 2D structure of Acetamiprid?

The 2D structure of Acetamiprid can be seen in Acetamiprid2d.png.

What is the Synonym for Acetamiprid D3?

The Synonym for Acetamiprid D3 is NI-25.

What is the molecular weight of Acetamiprid?

The molecular weight of Acetamiprid is 222.67 g/mol.

What is the IUPAC name of Acetamiprid?

The IUPAC name of Acetamiprid is N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide.