CAS
146987-10-2 Purity
Peak Area by HPLC ≥90%
146987-10-2 Purity
Peak Area by HPLC ≥90%
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Fmoc-Tyr(PO3H2)-OH
CAS
147762-53-6
Catalog Number
ACM147762536-1
Category
Amino Acids
Molecular Weight
483.41
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Specification
Description
A useful derivative for the synthesis of phosphotyrosine peptides by Fmoc SPPS. Pyrophosphate formation has been noted in peptides containing adjacent Tyr(PO3H2) residues. An evaluation of the optimal coupling conditions for introduction of this residue has been made.
Synonyms
Nα-Fmoc-O-phospho-L-tyrosine, N-α-Fmoc-O-phospho-L-tyrosine
Canonical SMILES
OC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC2c3ccccc3-c4ccccc24
InChI
1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m0/s1
InChI Key
AMXUJIHSMANWDW-QFIPXVFZSA-N
Application
Peptide synthesis.
Assay
≥95.0% (HPLC)
Beilstein
6674324
Color
white to off-white
Form
powder
Functional Group
Fmoc
MDL Number
MFCD00235902
NACRES
NA.26
PubChem ID
329747008
Quality Level
100
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
-20℃
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