Specification
Description
A modified lysine derivative for the preparation of chromogenically-labeled peptides by Fmoc SPPS. The Dabcyl group quenches the fluorescence of EDANS, Mca, TET, JOE, FAM fluorophores, making it an extremely useful tool for the synthesis of fluorescence-quenched peptide substrates.
Synonyms
Fmoc-Lys(Dabcyl)-OH
InChI
1S/C36H37N5O5/c1-41(2)27-20-18-26(19-21-27)40-39-25-16-14-24(15-17-25)34(42)37-22-8-7-13-33(35(43)44)38-36(45)46-23-32-30-11-5-3-9-28(30)29-10-4-6-12-31(29)32/h3-6,9-12,14-21,32-33H,7-8,13,22-23H2,1-2H3,(H,37,42)(H,38,45)(H,43,44)/t33-/m0/s1
InChI Key
FPOPWTDBGMLRNG-XIFFEERXSA-N
Application
Peptide synthesis.
Assay
≥95.5% (HPLC)
≥97% (TLC)
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Type
Standard Amino Acids, Dye Labeled, Lysine (Lys)