Decanethiol functionalized silver nanoparticles (AgNPs-SCH) represent a class of advanced functionalized nanomaterials with remarkable chemical and biological properties. These nanoparticles are modified by decanethiol, a long-chain alkanethiol molecule, which imparts unique surface chemistry, enhancing their stability, hydrophobicity, and bioactivity. Alfa Chemistry provides premium decanethiol functionalized silver nanoparticles that serve biomedical applications as well as optical and catalytic purposes.
| Catalog | Product Name | |
| ACMA00000346 | Decanethiol Functionalized Silver Nanoparticles Solution | Inquiry |
What Are Decanethiol Functionalized Silver Nanoparticles?
Decanethiol functionalized silver nanoparticles are synthesized by introducing decanethiol molecules onto the surface of silver nanoparticles through covalent bonding. The self-assembled monolayer created by decanethiol's long hydrophobic chain on nanoparticle surfaces enhances colloidal stability and prevents particle aggregation. The functionalization technique increases nanoparticle dispersibility while creating specific surface properties that expand their potential applications.
How Do Decanethiol Functionalized Silver Nanoparticles Improve Stability and Hydrophobicity?
Decanethiol molecules develop a protective monolayer around silver nanoparticles through strong Ag-S chemical bonds. This hydrophobic shell effectively prevents nanoparticle aggregation in solution, resulting in high colloidal stability. Additionally, the hydrophobic characteristic of decanethiol increases the nanoparticles' compatibility with non-polar solvents, which makes them fit for lipid-based systems and other hydrophobic environments.
We summarize some of the properties of decanethiol functionalized silver nanoparticles in the table below for reference.
| Property | Description |
| Surface Chemistry | Decanethiol monolayer via Ag–S bonds |
| Hydrophobicity | High, suitable for lipid-based systems |
| Stability | Excellent in physiological conditions |
| Antimicrobial Activity | Broad-spectrum antibacterial and antifungal effects |
| Optical Properties | Surface plasmon resonance (SPR) effect |
| Cytotoxicity | Low cytotoxicity at therapeutic concentrations |
What Are the Antimicrobial Applications of Decanethiol Functionalized Silver Nanoparticles?
Silver nanoparticles functionalized with decanethiol demonstrate strong antimicrobial properties which act against various bacterial and fungal species. The surface chemistry of nanoparticles disrupts microbial membranes, which causes cell death. Research indicates these nanoparticles can prevent antibiotic-resistant bacteria from growing, and thus they show potential for application in wound dressings and medical device coatings as antimicrobial agents.
The application of decanethiol functionalized silver nanoparticles for Leishmanicidal activity demonstrates promising results. Current research has shown that decanethiol functionalized silver nanoparticles can kill Leishmania species. Decanethiol functionalized silver nanoparticles demonstrated exceptional effectiveness against both promastigote and amastigote forms of the parasite at 0.04 µM, achieving a therapeutic index that surpassed conventional antimonial drugs by a factor of 20,000.
Fig.1 Chemical structure of an AgNp-SCH (a). Effect of nanoparticles and sodium stibogluconate (Sb) on the growth of L. mexicana (CL) (b), L. mexicana (DCL) (c), and L. major (d) promastigotes[1].
How Are Decanethiol Functionalized Silver Nanoparticles Used in Energy and Catalysis?
These nanoparticles serve essential functions in both energy conversion processes and catalytic systems. These materials serve as catalyst supports in proton exchange membrane fuel cells (PEMFC) to increase power density and catalytic efficiency. Their expansive surface area combined with surface plasmon resonance qualities enables these nanoparticles to serve as efficient photocatalysts that enhance visible-light-driven chemical reaction performance.
What Are Their Optical and Sensor Applications?
Decanethiol-functionalized silver nanoparticles are widely used in surface-enhanced Raman spectroscopy (SERS) for ultrasensitive molecular detection. The use of a monolayer coating boosts signal amplification and achieves detection thresholds down to 10-10 M. Their application extends to optical coatings, which enhance light transmission in both smart windows and optical devices.
Other Biomedical Applications of Decanethiol Functionalized Silver Nanoparticles
- Antimicrobial Coatings: Wound dressings and medical device coatings
- Drug Delivery Systems: Conjugation with drugs for targeted delivery
- Hyperthermia Therapy: Photothermal agents for cancer treatment
- Biosensing: Detection of biomolecules and pathogens
Decanethiol functionalized silver nanoparticles combine the intrinsic properties of silver nanoparticles with enhanced stability, hydrophobicity, and bioactivity conferred by decanethiol modification. Their use in antimicrobial treatments, energy systems, sensors, and biomedical sectors demonstrates their wide-ranging versatility. Alfa Chemistry offers high-quality functionalized nanoparticles, supporting cutting-edge research and industrial applications across multiple sectors. If you do not find what you need, please contact us.
Reference
- Isaac-Márquez A. P., et al. Decanethiol Functionalized Silver Nanoparticles are New Powerful Leishmanicidals in Vitro. World J Microbiol Biotechnol (2018).
