TES-1025

• CAS: 1883602-21-8
• Catalog Number: ACM1883602218
• Category: Inhibitors
• Molecular Weight: 383.44
• Molecular Formula: C18H13N3O3S2
• Description: TES-1025 is the first potent and selective inhibitor of human ACMSD (IC50 = 0.013 μM) that increases NAD+ levels in cellular systems. Defects in NAD+ homeostasis underpin a wide range of diseases, including cancer, metabolic disorders, and aging.
• Synonyms: TES-1025; TES 1025; TES1025
• IUPAC Name: 3-[[[5-cyano-1,6-dihydro-6-oxo-4-(2-thienyl)-2-pyrimidinyl]thio]methyl]phenylacetic acid
• Canonical SMILES: O=C(O)CC1=CC=CC(CSC2=NC(C3=CC=CS3)=C(C#N)C(N2)=O)=C1
• InChI: InChI=1S/C18H13N3O3S2/c19-9-13-16(14-5-2-6-25-14)20-18(21-17(13)24)26-10-12-4-1-3-11(7-12)8-15(22)23/h1-7H,8,10H2,(H,22,23)(H,20,21,24)
• InChI Key: RJQYGCGMQYVVIB-UHFFFAOYSA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 56.38; H, 3.42; N, 10.96; O, 12.52; S, 16.72
• Exact Mass: 383.0398
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).