N-Acetylneuraminic acid

• CAS: 131-48-6
• Catalog Number: ACM131486
• Category: Inhibitors
• Molecular Weight: 309.27
• Molecular Formula: C11H19NO9
• Description: N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies suggest that N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein recognition.
• Synonyms: Galactononulosonic acid
• IUPAC Name: (2S,4S,5R,6R)-5-Acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
• Canonical SMILES: CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)O)O
• InChI: InChI=1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11-/m0/s1
• InChI Key: SQVRNKJHWKZAKO-PFQGKNLYSA-N
• Boiling Point: 449.56 °C
• Melting Point: 184-186 °C
• Flash Point: 193 °C
• Density: 1.3580 g/cm³
• Appearance: Solid
• Storage: -20 °C
• Assay: 0.99
• Complexity: 403
• EC Number: 205-023-1
• Exact Mass: 309.10598118
• Isomeric SMILES: CC(=O)N[C@@H]1[C@H](C[C@](O[C@H]1[C@@H]([C@@H](CO)O)O)(C(=O)O)O)O
• MDL Number: MFCD00006620
• Monoisotopic Mass: 309.10598118
• Packaging: 1 kg
• pKa: 2.41±0.54(Predicted)
• Refractive Index: -32 ° (C=1, H₂O)
• Solubility In Water: 50 g/L (20 ºC)
• Stability: Stable. Incompatible with strong oxidizing agents.
• Storage Conditions: -20°C
• Topological Polar Surface Area: 177 Ų