Emodin-d4

• CAS: 132796-52-2
• Catalog Number: ACM132796522
• Category: Inhibitors
• Molecular Weight: 270.2369
• Molecular Formula: C₁₅H₁₀O₅
• Description: Emodin-d4 is the deuterium labeled Emodin. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice.
• Synonyms: Emodin-d4;1,3,8-Trihydroxy-6-Methyl-9,10-anthracenedione-d4;1,6,8-Trihydroxy-3-Methylanthraquinone-d4;4,5,7-Trihydroxy-2-Methyl-; anthraquinone-d4;Archin-d4;EModol-d4;Frangula EModin-d4;Frangulic Acid-d4
• IUPAC Name: 1,3,6,8-tetradeuterio-2,4,5-trihydroxy-7-methylanthracene-9,10-dione
• Canonical SMILES: O=C1C2=C(O)C([2H])=C(C)C([2H])=C2C(C3=C([2H])C(O)=C([2H])C(O)=C31)=O
• InChI Key: RHMXXJGYXNZAPX-QFFDRWTDSA-N
• Melting Point: 243-246°C
• Appearance: Brownish Solid
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Exact Mass: 274.07800
• H-Bond Acceptor: 5
• H-Bond Donor: 3
• Shipping: Can be shipped at room temperature, where not in use may vary.