Dexelvucitabine

• CAS: 134379-77-4
• Catalog Number: ACM134379774
• Category: Inhibitors
• Molecular Weight: 227.20
• Molecular Formula: C9H10FN3O3
• Description: Dexelvucitabine, also known as DPC-817; INCB-8721; PSI-5582; YZ-817, DOC-817, is a nucleoside reverse transcriptase inhibitor potentially for the treatment of HIV infection.
• Synonyms: Dexelvucitabine; beta-D-D-4FC; D-D-4FC; DFC; DPC-817; RVT; INCB-8721; PSI-5582; YZ-817; DOC-817
• IUPAC Name: 4-amino-5-fluoro-1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)pyrimidin-2(1H)-one
• Canonical SMILES: OC[C@@H]1C=C[C@H](N2C(N=C(C(F)=C2)N)=O)O1
• InChI: InChI=1S/C9H10FN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h1-3,5,7,14H,4H2,(H2,11,12,15)/t5-,7+/m0/s1
• InChI Key: HSBKFSPNDWWPSL-CAHLUQPWSA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Biological Target: Dexelvucitabine (Reverset), a cytidine analog, is a nucleoside reverse transcriptase inhibitor against HIV-1-resistant viruses containing a thymidine analog and/or M184V mutation in the viral polymerase. Dexelvucitabine is a 2'-deoxycytidine antiretroviral agent.
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 47.58; H, 4.44; F, 8.36; N, 18.50; O, 21.13
• Exact Mass: 227.0706
• HS Tariff Code: 2934.99.9001
• In Vitro Activity: TBD
• In Vivo Activity: TBD
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).