Iron(II) chloride

• CAS: 7758-94-3
• Catalog Number: ACM7758943-3
• Category: Main Products
• Molecular Weight: 126.75
• Molecular Formula: FeCl2
• Description: Iron(II) chloride, also known as ferrous chloride, is the chemical compound of formula FeCl2. It is a paramagnetic solid with a high melting point. The compound is white, but typical samples are often off-white.
• Synonyms: Ferrous chloride; Iron(II) chloride; 7758-94-3; Dichloroiron; FeCl2; Iron(2+) chloride; Iron (II) chloride; Iron(II)chloridetetrahydrate; Iron(II) chloride, anhydrous; Ferrous dichloride; Iron protochloride; Iron chloride (FeCl2); Iron(II) chloride (1:2); Fe(II) chloride; iron (11) chloride
• IUPAC Name: Dichloroiron
• Canonical SMILES: Cl[Fe]Cl
• InChI: InChI=1S/2ClH.Fe/h2*1H;/q;+2/p-2
• InChI Key: NMCUIPGRVMDVDB-UHFFFAOYSA-L
• Boiling Point: 1023 °C
• Melting Point: 677 °C
• Flash Point: 1023ºC
• Density: 3.16 g/mL at 25 °C (lit.)
• Solubility: Soluble in water, alcohol and acetone
• Appearance: Greenish white crystalline solid
• Application: Ferrous chloride (FeCl2) is used in pharmaceutical preparations, for sewage treatment, and as a mordant (which fixes dyes so that they will not run) in textiles.Aside from use in the laboratory synthesis of iron complexes, ferrous chloride serves as a coagulation and flocculation agent in wastewater treatment, especially for wastes containing chromate or sulfides.It is used for odor control in wastewater treatment. It is used as a precursor to make various grades of hematite that can be used in a variety of pigments. It is the precursor to hydrated iron(III) oxides that are magnetic pigments. FeCl2 finds some use as a reagent in organic synthesis.
• Complexity: 2.8
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Exact Mass: 125.872641
• Formal Charge: 0
• Hazard Statements: C:Corrosive
• Heavy Atom Count: 3
• Hydrogen Bond Acceptor Count: 0
• Hydrogen Bond Donor Count: 0
• Isotope Atom Count: 0
• Monoisotopic Mass: 125.872641
• Odor: Odorless
• Packing Group: III
• Rotatable Bond Count: 0
• Safety Description: S26-S36/37/39-S45
• Topological Polar Surface Area: 0 Ų
• Undefined Atom Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0

Case Study

Preparation of Iron-Diphosphine Complexes from Iron(II) Chloride for Catalytic Suzuki-Miyaura Coupling

Hatakeyama, Takuji, et al. Journal of the American Chemical Society, 2010, 132.31, 10674-10676.

The transition-metal-catalyzed cross-coupling reaction of organoboron compounds, known as Suzuki-Miyaura coupling, is one of the most prevalent organic synthetic reactions for the production of functional molecules, such as drug intermediates and organic electronic materials. In the presence of iron(II) chloride-diphosphine complexes and magnesium bromide, lithium arylborates react with primary and secondary alkyl halides to give the corresponding coupling products in good to excellent yields.
Iron(II) chloride-diphosphine complexes
· The iron(II) chloride-diphosphine complexes bear one o-phenylene-tethered diphosphine ligand possessing bulky substituents at the 3 and 5 positions of the diphenylphoshino groups.
· The bulky substituents were expected to introduce peripheral steric bulk around the iron center, preventing the formation of coordinatively saturated octahedral iron complexes.

Study on the hydration kinetics of iron(II) chloride

Böhm, Fabian, et al. Physical Chemistry Chemical Physics 17.29 (2015): 19582-19591.

Studied the hydration kinetics of solvated iron (II) and iron (III) chloride. For this purpose, THz/FIR absorption spectra of acidified FeCl2 and FeCl3 aqueous solutions were measured in the frequency range of 30-350cm-1 (E1-10THz). The non-linear concentration dependence of absorption was observed, which is attributed to the gradual formation of chloride complexes of Fe (II) and Fe (III), respectively. The molar extinction spectra of solvated species Fe2++2Cl and FeCl++Cl, as well as FeCl2++2Cl and FeCl2++Cl, were derived through principal component analysis of concentration dependent absorption spectra. In addition, the binding constants log KFeCl2=0.88 and log KFeCl3=0.32 for Fe2+and Cl with FeCl+were obtained, respectively. Simultaneous fitting was performed on all effective extinction spectra and their differences, including previous results on solvated manganese (II) chloride, nickel (II) chloride, and bromide. Therefore, the absorption peak can be assigned to the vibrational mode of the ion water complex.
Dissolve the weighed FeCl2 4H2O and FeCl3 6H2O in HPLC grade water solution. To prevent oxidation and hydroxide formation, all solutions were acidified with HCl to an H concentration of 1 M, corresponding to pH 0. To determine the water concentration in the sample, a density meter was used to measure the density at 20 ° C. Perform THz/FIR absorption measurements using an FTIR spectrometer. Throughout the entire measurement process, the sample chamber was continuously purged with industrial grade dry nitrogen gas to avoid the influence of air humidity. A high-precision thermostat that maintains a constant temperature of 20 ± 0.2 ℃ in the sample pool. For each individual spectrum, an average of 256 scans were performed with a resolution of 2cm. Place the sample solution in a standard liquid cell with a spacing of approximately 100 μ m between two parallel 4 mm thick TPX windows. 25mm thick. Before each measurement, use empty cells to determine the precise thickness of the sample layer.

Iron(II) chloride/isophthalic acid system catalyzed atom transfer radical polymerization

Zhu, Shenmin, and Deyue Yan. Macromolecules 33.22 (2000): 8233-8238.

Using ethyl o-bromopropionate as the initiator and Iron(II) chloride as the coordination catalyst, the atom transfer radical polymerization of methyl methacrylate was successfully initiated. The polymerization reaction was controlled at a molecular weight of 50,000. N,N-dimethylformamide is used to improve the solubility of the ligand. However, the amount of N,N-dimethylformamide did not have a significant effect on the active properties of the polymerization. Chain extension is performed to confirm the "living"/controlled nature of the polymerization system. The effects of different ferric chloride and ligand ratios on the polymerization reaction were investigated. In DMF, when the ratio of transition metal to ligand was 0.5, the initiation efficiency could reach 0.82. The easy availability and nontoxicity of isophthalic acid make it very attractive as a new ligand in iron-mediated ATRP.
Polymerization conversion was determined gravimetrically. Molecular weight and molecular weight distribution were measured on a PE Series 200 gel permeation chromatography (GPC) equipped with a hybrid 5 μ PS column and refractive index detector. All samples were run in THF at 25 °C at a flow rate of 1.0 mL/min; PMMA standards were used for calibration. 1H NMR spectra were recorded on an NMR spectrometer in CDCl3 at room temperature. Ultraviolet-visible (UV/Vis) spectral measurements were performed in DMF solution on a spectrophotometer. General procedure for homogeneous polymerization. In a typical embodiment, 2-bromopropionic acid ethyl ester (17.4 mg, 9.40 × 10 -3 mol/L), FeCl2 (23.9 mg, 1.88 10 -2 mol/L), MMA (5 mL, 4.7mol/L) and DMF (50% v/v) were added to a flask with a stirrer. Apply three rapid cycles of vacuum to nitrogen to remove oxygen, then degas the flask with nitrogen for 10 minutes. The mixture was stirred at room temperature until the catalyst was dissolved (half an hour). The flask was then immersed in an oil bath thermostat at 90 °C. After 10 hours, polymerization was stopped. The product was dissolved in THF. Finally, the resulting polymer was isolated by precipitation in methanol and dried under vacuum at 60 °C for 24 h. (The best way to isolate the polymer is to precipitate it in hexane, since low molecular weight PMMA is soluble in methanol.) Monomer conversion reaches about 89%,

Custom Q&A

What is the chemical formula of Iron(II) chloride?

The chemical formula of Iron(II) chloride is FeCl2.

Is Iron(II) chloride soluble in water?

Yes, Iron(II) chloride is soluble in water.

What is the molecular weight of Iron(II) chloride?

The molecular weight of Iron(II) chloride is 126.75 g/mol.

What is the IUPAC name of Iron(II) chloride?

The IUPAC name of Iron(II) chloride is dichloroiron.

What is the InChIKey of Iron(II) chloride?

The InChIKey of Iron(II) chloride is NMCUIPGRVMDVDB-UHFFFAOYSA-L.

What is the canonical SMILES of Iron(II) chloride?

The canonical SMILES of Iron(II) chloride is Cl[Fe]Cl.

What is the CAS number of Iron(II) chloride?

The CAS number of Iron(II) chloride is 7758-94-3.

Is Iron(II) chloride corrosive to metals?

Yes, Iron(II) chloride is corrosive to metals.

What are some synonyms of Iron(II) chloride?

Some synonyms of Iron(II) chloride are FERROUS CHLORIDE, Iron dichloride, and Dichloroiron.

What are some uses of Iron(II) chloride?

Iron(II) chloride is used in sewage treatment, dyeing of fabrics, and various other applications.