Boc-Asp(OcHx)-OH

• CAS: 73821-95-1
• Catalog Number: ACM73821951
• Category: Amino Acids
• Molecular Weight: 315.36
• Description: Standard building block for introduction of aspartic acid in Boc SPPS. Minimizes aspartimide formation, particularly in problematic sequences such as Asp-Gly.
• Synonyms: Boc-Asp(OcHx)-OH, N-α-t.-Boc-L-aspartic acid β-cyclohexyl ester
• InChI: 1S/C15H25NO6/c1-15(2,3)22-14(20)16-11(13(18)19)9-12(17)21-10-7-5-4-6-8-10/h10-11H,4-9H2,1-3H3,(H,16,20)(H,18,19)/t11-/m0/s1
• InChI Key: NLPQIWFEEKQBBN-NSHDSACASA-N
• Melting Point: 93-95℃
• Application: Peptide synthesis.
• Assay: ≥98% (TLC)
• Form: powder
• Functional Group: carboxylic acid
• MDL Number: MFCD00061996
• Quality Level: 200
• Reaction Suitability: reaction type: Boc solid-phase peptide synthesis
• Storage Temperature: 2-30℃

Synthetic Use

Upstream Synthesis Route 1

• 134757-75-8

• 73821-95-1

Reference: [1] Journal of Organic Chemistry, 1991, vol. 56, # 18, p. 5464 - 5466

Upstream Synthesis Route 2

• 24424-99-5
• 112259-66-2

• 73821-95-1

Reference: [1] Synthesis, 1992, # 4, p. 361 - 362

Downstream Synthesis Route 1

• 73821-95-1

• 13726-67-5

Reference: [1] Tetrahedron Letters, 2002, vol. 43, # 2, p. 311 - 313

* For details of the synthesis route, please refer to the original source to ensure accuracy.