Fmoc-Ser-OH

• CAS: 73724-45-5
• Catalog Number: ACM73724455-1
• Category: Amino Acids
• Molecular Weight: 327.33
• Description: Useful derivative for the synthesis of phosphoserine peptides by the Fmoc SPPS global phosphorylation methodology.
• Synonyms: Fmoc-Ser-OH, N-α-Fmoc-L-serine
• InChI: 1S/C18H17NO5/c20-9-16(17(21)22)19-18(23)24-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16,20H,9-10H2,(H,19,23)(H,21,22)/p-1/t16-/m0/s1
• InChI Key: JZTKZVJMSCONAK-INIZCTEOSA-M
• Melting Point: 80-90℃
• Application: Peptide synthesis.
• Assay: ≥92.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Form: powder
• Functional Group: hydroxyl
• MDL Number: MFCD00051928
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-30℃

Synthetic Use

Upstream Synthesis Route 1

• 129460-16-8

• 71989-33-8
• 73724-45-5

Reference: [1] Tetrahedron Letters, 2001, vol. 42, # 31, p. 5163 - 5165

Downstream Synthesis Route 1

• 67-56-1
• 73724-45-5

• 82911-78-2

Reference: [1] Arkivoc, 2016, vol. 2017, # 2, p. 260 - 271
[2] Organic letters, 2001, vol. 3, # 16, p. 2477 - 2479

Downstream Synthesis Route 2

• 73724-45-5

• 71989-33-8

Reference: [1] Tetrahedron Letters, 1992, vol. 33, # 49, p. 7605 - 7608

* For details of the synthesis route, please refer to the original source to ensure accuracy.