Fmoc-Nalpha-methyl-L-norvaline

Name: Fmoc-Nalpha-methyl-L-norvaline
SKU: ACM252049051-1
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CAS

252049-05-1

Catalog Number

ACM252049051-1

Category

Amino Acids

Molecular Weight

353.4

Molecular Formula

C21H23NO4

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Specification

Description

FMOC-Lys(Mtt)-OH is a derivative of lysine and is widely used in the field of chemistry and biochemistry. It is a white crystalline powder with a molecular weight of 545.66 g/mol. The compound is composed of two parts; the FMOC group and the Lys(Mtt) group. The FMOC group is a protecting group while the Lys(Mtt) group is a side chain of the amino acid lysine. The compound is commonly used as a building block in solid-phase peptide synthesis and a reagent for protein labeling for mass spectrometry.

Synonyms

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)pentanoic acid, FMOC-Lys(Mtt)-OH

IUPAC Name

(2S)-2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]pentanoic acid

Canonical SMILES

CCCC(C(=O)O)N(C)C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

InChI

1S/C21H23NO4/c1-3-8-19(20(23)24)22(2)21(25)26-13-18-16-11-6-4-9-14(16)15-10-5-7-12-17(15)18/h4-7,9-12,18-19H,3,8,13H2,1-2H3,(H,23,24)/t19-/m0/s1

InChI Key

HKELUUGCKFRJQM-IBGZPJMESA-N

Boiling Point

533.1±29.0 ℃at 760 mmHg

Melting Point

130.0 to 135.0 ℃

Flash Point

276.2±24.3 ℃

Density

1.2±0.1 g/cm³

Application

FMOC-Lys(Mtt)-OH has diverse applications in different scientific experiments. The compound is commonly used as a building block in solid-phase peptide synthesis, a reagent for protein labeling for mass spectrometry, and a protective group for amino acids. The compound has also been used in the synthesis of natural products and bioactive peptides.

Exact Mass

353.16272

Form

solid

Functional Group

Fmoc

HS Code

2935 90 90

LogP

5.09

PSA

66.84