Structure

Boc-Orn(Z)-OH

CAS
2480-93-5
Catalog Number
ACM2480935
Category
Amino Acids
Molecular Weight
366.41

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Specification

Description
Standard building block for introduction of ornithine amino-acid residues by Boc SPPS.
Synonyms
Boc-Orn(Z)-OH, N-α-t.-Boc-N-δ-benzyloxycarbonyl-L-ornithine
InChI
1S/C18H26N2O6/c1-18(2,3)26-17(24)20-14(15(21)22)10-7-11-19-16(23)25-12-13-8-5-4-6-9-13/h4-6,8-9,14H,7,10-12H2,1-3H3,(H,19,23)(H,20,24)(H,21,22)
InChI Key
QYYCZJUFHDLLOJ-UHFFFAOYSA-N
Application
Peptide synthesis.
Assay
≥98% (TLC)
≥99.0% (HPLC)
Form
powder
Functional Group
amine
MDL Number
MFCD00038259
Quality Level
200
Reaction Suitability
reaction type: Boc solid-phase peptide synthesis
Storage Temperature
2-30℃

Upstream Synthesis Route 1

  • 1070-19-5
  • 16937-91-0
  • 2480-93-5

Reference: [1]Bulletin of the Chemical Society of Japan,1966,vol. 39,p. 2242 - 2249

Upstream Synthesis Route 2

  • 16965-08-5
  • 3304-51-6
  • 2480-93-5

Reference: [1]Journal of the Chemical Society C: Organic,1967,p. 2632 - 2636

Downstream Synthesis Route 1

  • 2480-93-5
  • 16937-91-0

Reference: [1] Journal of Organic Chemistry, 2006, vol. 71, # 24, p. 9045 - 9050
[2] Beilstein Journal of Organic Chemistry, 2016, vol. 12, p. 564 - 570

Downstream Synthesis Route 2

  • 2480-93-5
  • 21887-64-9

Reference: [1] Journal of Medicinal Chemistry, 1996, vol. 39, # 23, p. 4531 - 4536

Downstream Synthesis Route 3

  • 2480-93-5
  • 21887-64-9

Reference: [1] Patent: US6262047, 2001, B1,

Downstream Synthesis Route 4

  • 2480-93-5
  • 21887-64-9

Reference: [1]Semple; Rowley; Brunck; Ha-Uong; Minami; Owens; Tamura; Goldman; Siev; Ardecky; Carpenter; Ge; Richard; Nolan; Hakanson; Tulinsky; Nutt; Ripka
[Journal of Medicinal Chemistry, 1996, vol. 39, # 23, p. 4531 - 4536]

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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