Specification
Description
A novel derivative for the introduction of dimethyl-lysine during Fmoc SPPS. Ref contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues.
Synonyms
Fmoc-Lys(Me)₂-OH HCl, N-α-Fmoc-N-ε-dimethyl-N-L-lysine · hydrochloride
InChI
1S/C23H28N2O4.ClH/c1-25(2)14-8-7-13-21(22(26)27)24-23(28)29-15-20-18-11-5-3-9-16(18)17-10-4-6-12-19(17)20;/h3-6,9-12,20-21H,7-8,13-15H2,1-2H3,(H,24,28)(H,26,27);1H/t21-;/m0./s1
InChI Key
SJFAFKDBWNFBCC-BOXHHOBZSA-N
Application
Peptide synthesis.
Assay
≥95% (TLC)
≥95.0% (HPLC)
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
-10 to -25℃
Type
Unusual Amino Acids, Methylated Amino Acids