UUN44923

• CAS: 2243944-92-3
• Catalog Number: ACM2243944923
• Category: Inhibitors
• Molecular Weight: 391.25
• Molecular Formula: C18H16Cl2N4O2
• Description: UUN44923 is a FTO inhibitor. UUN44923 may be useful for treating diseases assocd. with FTO targets, obesity, metabolic syndrome (MS)​, type 2 diabetes (T2D)​, Alzheimer's diseases, breast cancers, small-​cell lung cancers, a human bone marrow striated muscle cancer, a pancreatic cancer, malignant glioblastoma and the like. UUN44923 was reported in WO 2018157843.
• Synonyms: UUN44923; UUN-44923; UUN 44923; Dac51; Dac-51; Dac 51
• IUPAC Name: Benzamide, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]-N-hydroxy-
• Canonical SMILES: O=C(NO)C1=CC=CC=C1NC2=C(Cl)C=C(C3=C(C)NN=C3C)C=C2Cl
• InChI: InChI=1S/C18H16Cl2N4O2/c1-9-16(10(2)23-22-9)11-7-13(19)17(14(20)8-11)21-15-6-4-3-5-12(15)18(25)24-26/h3-8,21,26H,1-2H3,(H,22,23)(H,24,25)
• InChI Key: UMQKDDMRCQAIGA-UHFFFAOYSA-N
• Solubility: To be determined
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: To be determined
• Elemental Analysis: C, 55.26; H, 4.12; Cl, 18.12; N, 14.32; O, 8.18
• Exact Mass: 390.065
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).