FB23 inhibitor

• CAS: 2243736-35-6
• Catalog Number: ACM2243736356
• Category: Inhibitors
• Molecular Weight: 377.22
• Molecular Formula: C18H14Cl2N2O3
• Description: FB23 is a potent and selective inhibitor of N6-methyladenosine (m6A) demethylase FTO (fat mass and obesity associated protein). It moderately inhibits proliferation of NB4 and MONOMAC6 cells. FB23 demonstrates its potent inhibitory impact in AML models.
• Synonyms: FB23 inhibitor; FB-23; FB 23
• IUPAC Name: 2-[[2,6-Dichloro-4-(3,5-dimethyl-4-isoxazolyl)phenyl]amino]benzoic acid
• Canonical SMILES: O=C(O)C1=CC=CC=C1NC2=C(Cl)C=C(C3=C(C)ON=C3C)C=C2Cl
• InChI: InChI=1S/C18H14Cl2N2O3/c1-9-16(10(2)25-22-9)11-7-13(19)17(14(20)8-11)21-15-6-4-3-5-12(15)18(23)24/h3-8,21H,1-2H3,(H,23,24)
• InChI Key: VUXZATVQMFSUCM-UHFFFAOYSA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 57.31; H, 3.74; Cl, 18.80; N, 7.43; O, 12.72
• Exact Mass: 376.0381
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).