Tyrothricin

CAS

1404-88-2

Catalog Number

ACM1404882

Category

Inhibitors

Molecular Weight

179.17112

Molecular Formula

C65H85N11O13

MSDS COA Spec Sheet

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Specification

Description

Tyrothricin is a cyclic polypeptide-antibiotic mixture from Bacillus brevis. It is a locally effective antibiotic effective against gram-positive bacteria. It is sometimes combined with benzocaine 5mg to provide relief from sore throats. In systemic intake it can lead to severe side effects, therefore, the use is limited to topical application.Tyrothricin belongs to the pharmacologically related group of polypeptide antibiotic compounds including colistin, polymyxin B and bacitracin. There is no cross-resistance to these three agents.

Synonyms

bactratycin;coltirot;dermotricine;duboscrudecrystals;hydrotricine;intradermtyrothricin;martricin;soluthricin

Flash Point

871ºC

Density

1.32 g/cm³

Appearance

Solid

Storage

Powder-20°C, 3 years; In solvent-80°C. 6 months; -20°C, 1 month.

LogP

5.10700

PSA

379.75

Refractive Index

1.635

Safety Description

22-24/25

Shipping

Can be shipped at room temperature, where not in use may vary.

Source

Bacillus brevis

WGK Germany

What is the molecular formula of Tyrothricin?

The molecular formula of Tyrothricin is C65H85N11O13.

What is the molecular weight of Tyrothricin?

The molecular weight of Tyrothricin is 1228.4 g/mol.

How is Tyrothricin obtained?

Tyrothricin is obtained from Bacillus brevis, where it is a polypeptide antibiotic mixture.

What are the synonyms for Tyrothricin?

Some synonyms for Tyrothricin include Bactratycin, Dermotricine, Hydrotricine, Coltirot, Martricin.

How toxic is Tyrothricin?

Tyrothricin is very toxic to blood, liver, kidneys, meninges, and the olfactory apparatus.

How is Tyrothricin used?

Tyrothricin is used topically.

What is the IUPAC Name of Tyrothricin?

The IUPAC Name of Tyrothricin is 3-[(3R,6S,9S,12S,15S,17S,20S,22R,25S,28S)-20-(2-amino-2-oxoethyl)-9-(3-aminopropyl)-3,22,25-tribenzyl-15-[(4-hydroxyphenyl)methyl]-6-(2-methylpropyl)-2,5,8,11,14,18,21,24,27-nonaoxo-12-propan-2-yl-1,4,7,10,13,16,19,23,26-nonazabicyclo[26.3.0]hentriacontan-17-yl]propanoic acid.

What is the InChIKey of Tyrothricin?

The InChIKey of Tyrothricin is NLJVXZFCYKWXLH-DXTIXLATSA-N.

What is the CAS number of Tyrothricin?

The CAS number of Tyrothricin is 1404-88-2.

What is the ChEMBL ID of Tyrothricin?

The ChEMBL ID of Tyrothricin is CHEMBL577736.