Amphotericin b

• CAS: 1397-89-3
• Catalog Number: ACM1397893
• Category: Inhibitors
• Molecular Weight: 924.08
• Molecular Formula: C47H73NO17
• Description: Amphotericin B is an antifungal drug often used intravenously for serious systemic fungal infections and is the only effective treatment for some fungal infections.
• Synonyms: LNS-AmB;Amphocin;fungilin;ABELCET;AMBISOME
• Canonical SMILES: C[C@H]([C@@H](O)[C@@H](C)[C@H](C)OC1=O)/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](O[C@]2([H])O[C@H](C)[C@@H](O)[C@H](N)[C@@H]2O)C[C@@]3([H])[C@H](C(O)=O)[C@@H](O)C[C@](C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)C1)(O)O3
• Melting Point: >170ºC
• Flash Point: 643.5ºC
• Density: 1.34
• Appearance: Crystalline yellow solid
• Storage: 4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light).
• Hazard Codes: Xi
• Hazard Statements: C,Xi,Xn,T
• LogP: 1.41200
• MDL Number: MFCD00877763
• PSA: 319.61
• Refractive Index: 1.614
• RIDADR: UN 1759 8
• Safety Description: 26-36/37/39-45-36
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Source: Streptomyces nodosus
• Stability: Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
• Storage Conditions: 2-8ºC
• Supplemental Hazard Statements: H315-H319-H335
• Symbol: GHS07
• WGK Germany: 3

Custom Q&A

What is the molecular formula of amphotericin b according to the reference?

The molecular formula of amphotericin b is C47H73NO17.

What is the molecular weight of amphotericin b?

The molecular weight of amphotericin b is 924.1 g/mol.

What is the main role of amphotericin b?

Amphotericin b is a macrolide antibiotic used to treat potentially life-threatening fungal infections.

What is the IUPAC Name of amphotericin b?

The IUPAC Name of amphotericin b is (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid.

What is the InChIKey of amphotericin b?

The InChIKey of amphotericin b is APKFDSVGJQXUKY-INPOYWNPSA-N.

What is the Canonical SMILES of amphotericin b?

The Canonical SMILES of amphotericin b is CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O.

What is the CAS number of amphotericin b?

The CAS number of amphotericin b is 1397-89-3 and 30652-87-0.

For what infections is amphotericin b FDA-approved?

Amphotericin b is FDA-approved for the treatment of several types of fungal infections, such as histoplasmosis, cryptococcosis, and leishmaniasis.

What is the UNII of amphotericin b?

The UNII of amphotericin b is 7XU7A7DROE.

What is the ChEMBL ID of amphotericin b?

The ChEMBL ID of amphotericin b is CHEMBL267345.