TMPH inhibitor

• CAS: 849461-90-1
• Catalog Number: ACM849461901-1
• Category: Inhibitors
• Molecular Weight: 269.43
• Molecular Formula: C16H31NO2
• Description: TMPH is an inhibitor of CNS nicotinic receptor. Evaluation of nicotinic acetylcholine receptor (nAChR) subunits expressed in Xenopus laevis oocytes indicated that TMPH can produce a potent and long-lasting inhibition of neuronal nAChR formed by the pairwise combination of the most abundant neuronal α (i.e., α3 and α4) and β subunits (β2 and β4), with relatively little effect, because of rapid reversibility of inhibition, on muscle-type (α1β1γδ) or α7 receptors.
• Synonyms: TMPH; TMPH inhibitor
• IUPAC Name: 2,2,6,6-Tetramethyl-4-piperidinyl heptanoate
• Canonical SMILES: CCCCCCC(OC1CC(C)(C)NC(C)(C)C1)=O
• InChI: InChI=1S/C16H31NO2/c1-6-7-8-9-10-14(18)19-13-11-15(2,3)17-16(4,5)12-13/h13,17H,6-12H2,1-5H3
• InChI Key: PWWKJRFUJIFGGD-UHFFFAOYSA-N
• Solubility: To be determined
• Appearance: To be determined
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: To be determined
• Elemental Analysis: C, 71.33; H, 11.60; N, 5.20; O, 11.88
• Exact Mass: 269.2355
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).