Terbinafine hydrochloride

• CAS: 78628-80-5
• Catalog Number: ACM78628805
• Category: Inhibitors
• Molecular Weight: 327.89
• Molecular Formula: C₂₁H₂₆ClN
• Description: Terbinafine hydrochloride (TDT 067 hydrochloride) is an orally active and potent antifungal agent. Terbinafine hydrochloride is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine hydrochloride also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria.
• Synonyms: (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethylaminehydroc;lamosil;n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamin(e)-1-naphthalenemethanaminmon;n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamin(e)-1-naphthalenemethanaminmonohydrochloride;TERBINAFINE HCL;N-[(2E)-6,6-DIMETHYL-2-HEPTEN-4-YNYL]-N-METHYL-1-NAPHTHALENEMETHANAMINE;TRANS-N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-1-NAPHTHYLMETHYLAMINE HYDROCHLORIDE;(e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamine monohydrochloride
• Canonical SMILES: CN(C/C([H])=C([H])/C#CC(C)(C)C)CC1=CC=CC2=CC=CC=C21.[H]Cl
• Melting Point: 204-208°C
• Appearance: Solid
• Storage: 4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture).
• Hazard Statements: Xi,N
• Safety Description: 26-36/37/39-61-60
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Supplemental Hazard Statements: H315-H319-H335-H410
• Symbol: GHS07,GHS09

Custom Q&A

What is the molecular formula of terbinafine hydrochloride?

The molecular formula of terbinafine hydrochloride is C21H26ClN.

What is the molecular weight of terbinafine hydrochloride?

The molecular weight of terbinafine hydrochloride is 327.9 g/mol.

What is the synonym for terbinafine hydrochloride?

The synonym for terbinafine hydrochloride is Lamisil.

How is terbinafine hydrochloride obtained?

Terbinafine hydrochloride is obtained by the reaction of terbinafine with one molar equivalent of hydrogen chloride.

What is the role of terbinafine hydrochloride?

Terbinafine hydrochloride has a role as an EC 1.14.13.132 (squalene monooxygenase) inhibitor and a P450 inhibitor.

What is the medical use of terbinafine hydrochloride?

Terbinafine hydrochloride is used to treat dermatomycoses of the skin and nails.

What is the IUPAC name of terbinafine hydrochloride?

The IUPAC name of terbinafine hydrochloride is (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine;hydrochloride.

What is the InChIKey of terbinafine hydrochloride?

The InChIKey of terbinafine hydrochloride is BWMISRWJRUSYEX-SZKNIZGXSA-N.

What is the CAS number of terbinafine hydrochloride?

The CAS number of terbinafine hydrochloride is 78628-80-5.

What is the ChEMBL ID of terbinafine hydrochloride?

The ChEMBL ID of terbinafine hydrochloride is CHEMBL1200832.