CAS
443683-76-9 Purity
98%
443683-76-9 Purity
98%
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Rosiglitazone hydrochloride
CAS
302543-62-0
Catalog Number
ACM302543620
Category
Inhibitors
Molecular Weight
393.89
Molecular Formula
C18H19N3O3S.HCl
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Specification
Description
Rosiglitazone (BRL 49653) hydrochloride is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). Rosiglitazone hydrochloride is a TRPC5 activator (EC50: 30 μM) and TRPM3 inhibitor. Rosiglitazone hydrochloride can be used in the research of obesity and diabetes, senescence, ovarian cancer.
Synonyms
5-[4-[2-[N-Methyl-N- (pyridinyl) amino]ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride
IUPAC Name
5-[[4-[2-[Methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrochloride
Canonical SMILES
CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.Cl
InChI
InChI=1S/C18H19N3O3S.ClH/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;/h2-9,15H,10-12H2,1H3,(H,20,22,23);1H
InChI Key
XRSCTTPDKURIIJ-UHFFFAOYSA-N
Appearance
Powder
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