Structure

Dacarbazine

CAS
4342-03-4
Catalog Number
ACM4342034
Category
Inhibitors
Molecular Weight
182.18
Molecular Formula
C6H10N6O

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Specification

Description
Dacarbazine is a cell cycle nonspecific antineoplastic alkylating agent. Dacarbazine inhibits T and B lymphoblastic response, with IC50 values of 50 and 10 μg/ml, respectively. Dacarbazine can be used for the research of metastatic malignant melanoma.
Synonyms
4-(3,3-Dimethyl-1-triazeno)imidazole-5-carboxamide
IUPAC Name
4-[(E)-dimethylaminodiazenyl]-1H-imidazole-5-carboxamide
Canonical SMILES
CN(C)/N=N/C1=C(NC=N1)C(=O)N
InChI
InChI=1S/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9)/b11-10+
InChI Key
FDKXTQMXEQVLRF-ZHACJKMWSA-N
Boiling Point
315.57 °C
Melting Point
199-205 °C
Density
1.32 g/ml
Appearance
White powder
Storage
4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light).
pKa
4.42
Shipping
Can be shipped at room temperature, where not in use may vary.
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