Piflufolastat

CAS
1423758-00-2
Catalog Number
ACM1423758002
Category
Others
Molecular Weight
442.40
Molecular Formula
C18H23FN4O8

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Specification

Description
Piflufolastat, also known as DCFPYL is a PSMA-targeted PET imaging agent for prostate cancer. Piflufolastat F-18 is a radioactive diagnostic agent used for positron emission tomography (PET) imaging. It was approved in 2021. Piflufolastat we are supplying is not radio-label compound.
Synonyms
DCFPYL; Piflufolastat
IUPAC Name
(((S)-1-carboxy-5-(6-fluoronicotinamido)pentyl)carbamoyl)-L-glutamic acid
Canonical SMILES
O=C(O)CC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCCCNC(C1=CC=C(F)N=C1)=O)=O
InChI
InChI=1S/C18H23FN4O8/c19-13-6-4-10(9-21-13)15(26)20-8-2-1-3-11(16(27)28)22-18(31)23-12(17(29)30)5-7-14(24)25/h4,6,9,11-12H,1-3,5,7-8H2,(H,20,26)(H,24,25)(H,27,28)(H,29,30)(H2,22,23,31)/t11-,12-/m0/s1
InChI Key
OLWVRJUNLXQDSP-RYUDHWBXSA-N
Solubility
Soluble in DMSO
Appearance
Solid powder
Shelf Life
>3 years if stored properly
Storage
Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
Alternative CAS
1207181-29-0 (F18); 1423758-00-2 (F-19)
Biological Target
Piflufolastat, also known as DCFPYL is a PSMA-targeted PET imaging agent for prostate cancer.
Drug Formulation
This drug may be formulated in DMSO
Elemental Analysis
C, 48.87; H, 5.24; F, 4.29; N, 12.66; O, 28.93
Exact Mass
442.15
HS Tariff Code
2934.99.03.00
In Vitro Activity
TBD
In Vivo Activity
TBD
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Stock Solution Storage
0-4 °C for short term (days to weeks), or -20 °C for long term (months).
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