GJ-103 free acid

• CAS: 1459687-89-8
• Catalog Number: ACM1459687898
• Category: Others
• Molecular Weight: 342.37
• Molecular Formula: C16H14N4O3S
• Description: GJ-103 is an active analog of the read-through compound GJ072. Chemical-induced read through of premature stop codons might be exploited as a potential treatment strategy for genetic disorders caused by nonsense mutations.
• Synonyms: GJ-103 free acid; GJ103; GJ 103; GJ-103
• IUPAC Name: 2-((4-(3-methoxyphenyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid
• Canonical SMILES: O=C(O)CSC1=NN=C(C2=NC=CC=C2)N1C3=CC=CC(OC)=C3
• InChI: InChI=1S/C16H14N4O3S/c1-23-12-6-4-5-11(9-12)20-15(13-7-2-3-8-17-13)18-19-16(20)24-10-14(21)22/h2-9H,10H2,1H3,(H,21,22)
• InChI Key: GBVQSAZHPCDBDY-UHFFFAOYSA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 1459687-96-7 (sodium); 1459687-89-8 (free acid)
• Biological Target: GJ-103 is an active analog of the read-through compound GJ072.
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 56.13; H, 4.12; N, 16.36; O, 14.02; S, 9.36
• Exact Mass: 342.0787
• HS Tariff Code: 2934.99.9001
• In Vitro Activity: TBD
• In Vivo Activity: TBD
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).