PI-103

• CAS: 371935-74-9
• Catalog Number: ACM371935749
• Category: Inhibitors
• Molecular Weight: 384.82
• Molecular Formula: C19H17ClN4O3
• Description: PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α), and mTOR.
• Synonyms: PI103; PI-103; PI 103
• IUPAC Name: 3-(4-morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol
• Canonical SMILES: OC1=CC=CC(C2=NC(N3CCOCC3)=C(OC4=NC=CC=C45)C5=N2)=C1
• InChI: InChI=1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2
• InChI Key: TUVCWJQQGGETHL-UHFFFAOYSA-N
• Solubility: Soluble in DMSO, not in water
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 371935-74-9 (free base); 371935-79-4 (HCl)
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 59.30; H, 4.45; Cl, 9.21; N, 14.56; O, 12.47
• Exact Mass: 384.09892
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).