Lopinavir

• CAS: 192725-17-0
• Catalog Number: ACM192725170
• Category: Inhibitors
• Molecular Weight: 628.8
• Molecular Formula: C37H48N4O5
• Description: Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 μM.
• Synonyms: (2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
• IUPAC Name: (2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
• Canonical SMILES: CC1=C(C(=CC=C1)C)OCC(=O)N[C@@H](CC2=CC=CC=C2)[C@H](C[C@H](CC3=CC=CC=C3)NC(=O)[C@H](C(C)C)N4CCCNC4=O)O
• InChI: InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
• InChI Key: KJHKTHWMRKYKJE-SUGCFTRWSA-N
• Appearance: White to off-white solid

Custom Q&A

What is the PubChem CID for Gold sodium cyanide?

The PubChem CID for Gold sodium cyanide is 167274.

What is the molecular formula of Gold sodium cyanide?

The molecular formula of Gold sodium cyanide is NaAu(CN)2.

What is the molecular weight of Gold sodium cyanide?

The molecular weight of Gold sodium cyanide is 271.99 g/mol.

What are the synonyms for Gold sodium cyanide?

The synonyms for Gold sodium cyanide are Sodium gold cyanide, Sodium dicyanoaurate, GOLD SODIUM CYANIDE, sodium;gold(1+);dicyanide.

What is the IUPAC name of Gold sodium cyanide?

The IUPAC name of Gold sodium cyanide is sodium;gold(1+);dicyanide.

What is the InChI key of Gold sodium cyanide?

The InChI key of Gold sodium cyanide is VMDSWYDTKFSTQH-UHFFFAOYSA-N.

What is the CAS number of Gold sodium cyanide?

The CAS number of Gold sodium cyanide is 15280-09-8.

What is the hydrogen bond donor count of Gold sodium cyanide?

The hydrogen bond donor count of Gold sodium cyanide is 0.

What is the hydrogen bond acceptor count of Gold sodium cyanide?

The hydrogen bond acceptor count of Gold sodium cyanide is 4.

Is Gold sodium cyanide a canonicalized compound?

Yes, Gold sodium cyanide is a canonicalized compound according to PubChem.