INE963

• CAS: 2640567-43-5
• Catalog Number: ACM2640567435
• Category: Inhibitors
• Molecular Weight: 402.52
• Molecular Formula: C19H26N6O2S
• Description: INE963 is a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria. INE963 demonstrates potent cellular activity against Pf 3D7 (EC50 = 0.006 μM) and achieves "artemisinin-like" kill kinetics in vitro with a parasite clearance time of <24 h.
• Synonyms: INE963; INE 963; INE-963
• IUPAC Name: 4-(aminomethyl)-1-(5-(6-isopropyl-2-methoxypyridin-3-yl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl)piperidin-4-ol
• Canonical SMILES: OC1(CN)CCN(C2=NN3C(S2)=NC=C3C4=C(OC)N=C(C(C)C)C=C4)CC1
• InChI: InChI=1S/C19H26N6O2S/c1-12(2)14-5-4-13(16(22-14)27-3)15-10-21-17-25(15)23-18(28-17)24-8-6-19(26,11-20)7-9-24/h4-5,10,12,26H,6-9,11,20H2,1-3H3
• InChI Key: JYHSRMKXBAPFST-UHFFFAOYSA-N
• Solubility: To be determined
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: To be determined
• Elemental Analysis: C, 56.70; H, 6.51; N, 20.88; O, 7.95; S, 7.96
• Exact Mass: 402.1838
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).