Fmoc-Pro-OH

• CAS: 71989-31-6
• Catalog Number: ACM71989316
• Category: Amino Acids
• Molecular Weight: 337.37
• Molecular Formula: C20H19NO4
• Description: High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.; Standard building block for introduction of proline amino-acid residues by Fmoc SPPS.
• Synonyms: Fmoc-Pro-OH, N-α-Fmoc-L-proline
• InChI: 1S/C20H19NO4/c22-19(23)18-10-5-11-21(18)20(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,22,23)
• InChI Key: ZPGDWQNBZYOZTI-UHFFFAOYSA-N
• Melting Point: 112-115℃
• Application: Peptide synthesis.
• Assay: ≥94.0% (acidimetric); ≥98% (TLC); ≥99.0% (HPLC)
• Form: powder
• Functional Group: Fmoc
• MDL Number: MFCD00037122
• Quality Level: 400
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-30℃
• Type: Unlabeled Standard Amino Acids, Proline (Pro)

Synthetic Use

Downstream Synthesis Route 1

• 29022-11-5
• 35661-60-0
• 1403834-74-1
• 71989-31-6
• 71989-23-6
• 71989-38-3
• 132388-59-1
• 132327-80-1

• 50-56-6

Reference: [1] Organic Letters, 2013, vol. 15, # 3, p. 616 - 619

Downstream Synthesis Route 2

• 29022-11-5
• 35661-60-0
• 71989-31-6
• 71989-23-6
• 71989-38-3
• 103213-32-7
• 132388-59-1
• 132327-80-1

• 50-56-6

Reference: [1] Organic Letters, 2018, vol. 20, # 19, p. 6074 - 6078

Downstream Synthesis Route 3

• 71989-31-6
• 100-52-7

• 31795-93-4

Reference: [1] Tetrahedron Letters, 1996, vol. 37, # 27, p. 4819 - 4822

* For details of the synthesis route, please refer to the original source to ensure accuracy.