Specification
Description
Fmoc-Oic-OH (2R,3aR,7aR) is a synthetic amino acid that is used in the synthesis of peptides and proteins. It is a derivative of Oic acid, which is a non-standard amino acid that is commonly found in various natural products. Fmoc-Oic-OH (2R,3aR,7aR) is used in solid-phase peptide synthesis due to its compatibility with Fmoc-based protection and deprotection protocols.
Synonyms
Fmoc-Oic-OH (2R,3aR,7aR)
IUPAC Name
(2R,3aR,7aR)-1-(9H-fluoren-9-ylmethoxycarbonyl)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
Canonical SMILES
C1CCC2C(C1)CC(N2C(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)C(=O)O
InChI
1S/C24H25NO4/c26-23(27)22-13-15-7-1-6-12-21(15)25(22)24(28)29-14-20-18-10-4-2-8-16(18)17-9-3-5-11-19(17)20/h2-5,8-11,15,20-22H,1,6-7,12-14H2,(H,26,27)/t15-,21-,22-/m1/s1
InChI Key
JBZXLQHJZHITMW-UJUVCNOISA-N
Boiling Point
592.4±33.0 ℃at 760 mmHg
Application
Fmoc-Oic-OH (2R,3aR,7aR) has a wide range of applications in scientific experiments, such as the synthesis of peptides and proteins, the study of protein-protein interactions, and the development of new drugs.
Type
Unusual Amino Acids, Analogs of Proline
Vapor Pressure
0.0±1.8 mmHg at 25℃