Fmoc-Glu(OAll)-OH

• CAS: 133464-46-7
• Catalog Number: ACM133464467
• Category: Amino Acids
• Molecular Weight: 409.43
• Molecular Formula: C23H23NO6
• Description: Orthogonally-protected building block for the synthesis of peptides modified at the Glu side chain by Fmoc SPPS.
• Synonyms: Fmoc-Glu(OAll)-OH
• InChI: 1S/C23H23NO6/c1-2-13-29-21(25)12-11-20(22(26)27)24-23(28)30-14-19-17-9-5-3-7-15(17)16-8-4-6-10-18(16)19/h2-10,19-20H,1,11-14H2,(H,24,28)(H,26,27)/t20-/m0/s1
• InChI Key: LRBARFFNYOKIAX-FQEVSTJZSA-N
• Application: Peptide synthesis.
• Assay: ≥97.0% (HPLC); ≥97.0% (acidimetric); ≥98% (TLC)
• Form: powder
• Functional Group: carboxylic acid
• MDL Number: MFCD00190879
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-30℃
• Type: Unusual Amino Acids, Analogs of Aspartic and Glutamic Acids

Synthetic Use

Upstream Synthesis Route 1

• 82911-69-1

• 133464-46-7

Reference: [1] Angewandte Chemie - International Edition, 2007, vol. 46, # 14, p. 2478 - 2484
[2] Journal of the Chemical Society - Perkin Transactions 1, 1998, # 9, p. 1467 - 1474
[3] Chemistry - A European Journal, 2005, vol. 11, # 9, p. 2756 - 2772

Upstream Synthesis Route 2

• 1159497-09-2

• 133464-46-7

Reference: [1] Tetrahedron Letters, 2009, vol. 50, # 23, p. 2719 - 2721

Upstream Synthesis Route 3

• 28920-43-6

• 133464-46-7

Reference: [1] Bioorganic and Medicinal Chemistry, 1997, vol. 5, # 1, p. 165 - 177