Specification
Description
Standard building block of introduction of D-histidine amino-acid residues by Fmoc SPPS.
Synonyms
Fmoc-N(im)-trityl-D-histidine
Canonical SMILES
OC(=O)[C@@H](Cc1cn(cn1)C(c2ccccc2)(c3ccccc3)c4ccccc4)NC(=O)OCC5c6ccccc6-c7ccccc57
InChI
1S/C40H33N3O4/c44-38(45)37(42-39(46)47-26-36-34-22-12-10-20-32(34)33-21-11-13-23-35(33)36)24-31-25-43(27-41-31)40(28-14-4-1-5-15-28,29-16-6-2-7-17-29)30-18-8-3-9-19-30/h1-23,25,27,36-37H,24,26H2,(H,42,46)(H,44,45)/t37-/m1/s1
InChI Key
XXMYDXUIZKNHDT-DIPNUNPCSA-N
Application
Peptide synthesis.
Optical Activity
[α]22/D -85.0°, c = 1% in chloroform
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Type
Unlabeled Standard Amino Acids, Histidine (His)