Structure

Diosgenin Glucoside

CAS
14144-06-0
Catalog Number
ACM14144060
Category
Inhibitors
Molecular Weight
576.77
Molecular Formula
C33H52O8

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Specification

Description
Diosgenin glucoside, a saponin compound extracted from Trillium tschonoskii, provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis .
Synonyms
(25R)-3β-(β-D-Glucopyranosyloxy)spirost-5-ene
IUPAC Name
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxyoxane-3,4,5-triol
Canonical SMILES
C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)C)C)C)OC1
InChI
InChI=1S/C33H52O8/c1-17-7-12-33(38-16-17)18(2)26-24(41-33)14-23-21-6-5-19-13-20(8-10-31(19,3)22(21)9-11-32(23,26)4)39-30-29(37)28(36)27(35)25(15-34)40-30/h5,17-18,20-30,34-37H,6-16H2,1-4H3/t17-,18+,20+,21-,22+,23+,24+,25-,26+,27-,28+,29-,30-,31+,32+,33-/m1/s1
InChI Key
WXMARHKAXWRNDM-GAMIEDRGSA-N
Boiling Point
705.1±60.0 °C
Melting Point
275-280 °C
Density
1.27±0.1 g/ml
Appearance
Powder
Storage
4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light).
pKa
12.91±0.70
Shipping
Can be shipped at room temperature, where not in use may vary.
Source
PlantsLiliaceae Trillium tschonoskii Maxim.
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