(Z)-Guggulsterone

• CAS: 39025-23-5
• Catalog Number: ACM39025235-1
• Category: Inhibitors
• Molecular Weight: 312.45
• Molecular Formula: C21H28O2
• Description: (Z)-Guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. (Z)-Guggulsterone inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling axis. (Z)-Guggulsterone is also a potent FXR antagonist. (Z)-Guggulsterone reduces ACE2 expression and SARS-CoV-2 infection.

Custom Q&A

What is the molecular formula of (Z)-Guggulsterone?

The molecular formula of (Z)-Guggulsterone is C21H28O2.

What is the molecular weight of (Z)-Guggulsterone?

The molecular weight of (Z)-Guggulsterone is 312.4 g/mol.

What is the IUPAC name of (Z)-Guggulsterone?

The IUPAC name of (Z)-Guggulsterone is (8R,9S,10R,13S,14S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione.

What is the InChI of (Z)-Guggulsterone?

The InChI of (Z)-Guggulsterone is InChI=1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1.

What is the InChIKey of (Z)-Guggulsterone?

The InChIKey of (Z)-Guggulsterone is WDXRGPWQVHZTQJ-OSJVMJFVSA-N.

What is the canonical SMILES of (Z)-Guggulsterone?

The canonical SMILES of (Z)-Guggulsterone is CC=C1C(=O)CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C.

What is the isomeric SMILES of (Z)-Guggulsterone?

The isomeric SMILES of (Z)-Guggulsterone is C/C=C/1\C(=O)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C.

What is the CAS number of (Z)-Guggulsterone?

The CAS number of (Z)-Guggulsterone is 39025-23-5.

What is the XLogP3-AA value of (Z)-Guggulsterone?

The XLogP3-AA value of (Z)-Guggulsterone is 3.9.

What is the topological polar surface area of (Z)-Guggulsterone?

The topological polar surface area of (Z)-Guggulsterone is 34.1Ų.