Specification
Description
β-Lapachone (ARQ-501;NSC-26326) is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression.
Synonyms
3,4-Dihydro-2,2-Dimethyl-2H-Naphtho[1,2-B]Pyran-5,6-Dione
IUPAC Name
2,2-dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dione
Canonical SMILES
CC1(CCC2=C(O1)C3=CC=CC=C3C(=O)C2=O)C
InChI
InChI=1S/C15H14O3/c1-15(2)8-7-11-13(17)12(16)9-5-3-4-6-10(9)14(11)18-15/h3-6H,7-8H2,1-2H3
InChI Key
QZPQTZZNNJUOLS-UHFFFAOYSA-N
Boiling Point
381.4±42.0 °C at 760 mmHg
Melting Point
>110 ºC (dec.)
Flash Point
169.7±27.9 °C