Lamivudine

• CAS: 134678-17-4
• Catalog Number: ACM134678174
• Category: Inhibitors
• Molecular Weight: 229.26
• Molecular Formula: C₈H₁₁N₃O₃S
• Description: Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS.
• Synonyms: (-)-BCH-189;(-)-BETA-L-2,3-DIDEOXY-3-THIACYTIDINE;(-)-B-L-2,3-DIDEOXY-3-THIACYTIDINE;(2r-cis)-4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1h)-pyrimidinone;2-deoxy-3-thiacytidine;4-AMINO-1-((2R,5S)-2-HYDROXYMETHYL-[1,3]OXATHIOLAN-5-YL)-1H-PYRIMIDIN-2-ONE;3TC;3-THIA-2,3-DIDEOXYCYTIDINE
• Canonical SMILES: OC[C@H]1SC[C@@H](N2C(N=C(N)C=C2)=O)O1
• Melting Point: 177°C
• Appearance: Solid
• Storage: Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Supplemental Hazard Statements: H361-H225-H301+H311+H331-H370
• Symbol: GHS02,GHS06,GHS08

Custom Q&A

What is the molecular formula of Lamivudine?

The molecular formula of Lamivudine is C8H11N3O3S.

What is the molecular weight of Lamivudine?

The molecular weight of Lamivudine is 229.26 g/mol.

What is the IUPAC Name of Lamivudine?

The IUPAC Name of Lamivudine is 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one.

What is the InChIKey of Lamivudine?

The InChIKey of Lamivudine is JTEGQNOMFQHVDC-NKWVEPMBSA-N.

How is Lamivudine related to HIV-1?

Lamivudine is an inhibitor of HIV-1 reverse transcriptase and is used as an antiviral in the treatment of AIDS.

What is the primary function of Lamivudine?

Lamivudine is a HIV-1 reverse transcriptase inhibitor, an antiviral drug, and an anti-HBV agent.

In what year was Lamivudine first created?

Lamivudine was first created in 2005.

What is the CAS number of Lamivudine?

The CAS number of Lamivudine is 134678-17-4.

Can Lamivudine be used alone to treat HIV?

No, Lamivudine is always used in combination with other HIV medicines for the treatment of HIV infection.

What is the role of Lamivudine in the treatment of hepatitis B?

Lamivudine is used as an antiviral in the treatment of hepatitis B.