Boc-Tyr(tBu)-OH

CAS
47375-34-8
Catalog Number
ACM47375348-1
Category
Amino Acids
Molecular Weight
337.41
Molecular Formula
C18H27NO5

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Specification

Description
Useful building block for introduction of N-terminal tyrosine residues in Fmoc SPPS.
Synonyms
Boc-Tyr(tBu)-OH, N-α-t.-Boc-O-t.-butyl-L-tyrosine
InChI
1S/C18H27NO5/c1-17(2,3)23-13-9-7-12(8-10-13)11-14(15(20)21)19-16(22)24-18(4,5)6/h7-10,14H,11H2,1-6H3,(H,19,22)(H,20,21)/t14-/m0/s1
InChI Key
ZEQLLMOXFVKKCN-AWEZNQCLSA-N
Melting Point
113-116℃
Application
Peptide synthesis.
Assay
≥98% (TLC)
Form
powder
Functional Group
hydroxyl
MDL Number
MFCD00065598
Quality Level
200
Reaction Suitability
reaction type: Boc solid-phase peptide synthesis
Storage Temperature
2-30℃
Type
Unlabeled Standard Amino Acids, Tyrosine (Tyr)

Upstream Synthesis Route 1

  • 24424-99-5
  • 4727-00-8
  • 47375-34-8

Reference: [1] Journal of the American Chemical Society, 2014, vol. 136, # 28, p. 9890 - 9893

Upstream Synthesis Route 2

  • 24424-95-1
  • 4727-00-8
  • 47375-34-8

Reference: [1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983, # 1, p. 65 - 73

Upstream Synthesis Route 3

  • 24424-95-1
  • 4727-00-8
  • 47375-34-8

Reference: [1]Journal of the Chemical Society. Perkin transactions I,1983,p. 65 - 73

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