m-Fluoro-DL-phenylalanine

• CAS: 456-88-2
• Catalog Number: ACM456882-1
• Category: Amino Acids
• Molecular Weight: 183.18
• Molecular Formula: FC6H4CH2CH(NH2)COOH
• Synonyms: 3-Fluoro-DL-phenylalanine
• Canonical SMILES: NC(Cc1cccc(F)c1)C(O)=O
• InChI: 1S/C9H10FNO2/c10-7-3-1-2-6(4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
• InChI Key: VWHRYODZTDMVSS-UHFFFAOYSA-N
• Melting Point: 240-250℃
• Application: cell analysis; peptide synthesis
• Assay: ≥98%
• Beilstein: 2939807
• Biochem Physiol Actions: m-Fluoro-DL-phenylalanine, a toxic antimetabolite, is a racemic mixture of a substituted (halogenated) benzoyl D and L phenylalanine with potential use in antiviral and antimicrobial drug development.
• Color: white to off-white
• EC Number: 220-104-1
• Form: powder
• MDL Number: MFCD00004273
• PubChem ID: 24894882
• Quality Level: 200
• Storage Temperature: 2-8℃

Synthetic Use

Upstream Synthesis Route 1

• 380-70-1

• 456-88-2

Reference: [1] European Journal of Medicinal Chemistry, 2018, vol. 143, p. 1325 - 1344
[2] Journal of the American Chemical Society, 1950, vol. 72, p. 1806
[3] Organic Letters, 2018, vol. 20, # 19, p. 6298 - 6301

Upstream Synthesis Route 2

• 207910-83-6

• 456-88-2

Reference: [1] Organic and Biomolecular Chemistry, 2004, vol. 2, # 18, p. 2684 - 2691

Upstream Synthesis Route 3

• 456-42-8

• 456-88-2

Reference: [1] Organic and Biomolecular Chemistry, 2004, vol. 2, # 18, p. 2684 - 2691

Upstream Synthesis Route 4

• 143051-43-8

• 456-88-2

Reference: [1]Journal of the American Chemical Society,1950,vol. 72,p. 1806

Upstream Synthesis Route 5

• 17607-28-2

• 456-88-2

Reference: [1]Journal of the American Chemical Society,1950,vol. 72,p. 1806

Downstream Synthesis Route 1

• 456-88-2

• 404-70-6

Reference: [1]Journal fur praktische Chemie (Leipzig 1954),1932,vol. <2> 135,p. 101,113

* For details of the synthesis route, please refer to the original source to ensure accuracy.