(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde

• CAS: 15186-48-8
• Catalog Number: ACM15186488
• Category: Main Products
• Molecular Weight: 130.14
• Molecular Formula: C₆H₁₀O₃
• Synonyms: (R)-2,2-DIMETHYL-[1,3]DIOXOLANE-4-CARBALDEHYDE;(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXALDEHYDE;(R)-2,3-ISOPROPYLIDENE GLYCERALDEHYDE;1,3-DIOXOLANE-4-CARBOXALDEHYDE, 2,2-DIMETHYL-, (R)-;2,3-O-ISOPROPYLIDENE-D-GLYCERALDEHYDE;2,3-O-(R)-ISOPROPYLIDENE-L-GLYCERALDEHYDE;(4R)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBALDEHYDE;D-(R)-GLYCERALDEHYDE ACETONIDE
• IUPAC Name: (4R)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde
• Canonical SMILES: CC1(OCC(O1)C=O)C
• InChI Key: YSGPYVWACGYQDJ-YFKPBYRVSA-N
• Boiling Point: 139°C(lit.)
• Flash Point: 143°F
• Density: 1.045g/mL at 25°C(lit.)
• Appearance: Oily liquid
• Exact Mass: 130.06300
• Supplemental Hazard Statements: H227-H303-H333-H351
• Symbol: GHS08
• WGK Germany: 3

Synthetic Use

Upstream Synthesis Route 1

• 1707-77-3

• 15186-48-8

Reference: [1]Lorca, Miguel; Kuhn, Dan; Kurosu, Michio
[Tetrahedron Letters, 2001, vol. 42, # 36, p. 6243 - 6246]

Upstream Synthesis Route 2

• 52373-72-5

• 15186-48-8

Reference: [1]Jiang; Ma
[Synthetic Communications, 1995, vol. 25, # 22, p. 3641 - 3645]

Downstream Synthesis Route 1

• 15186-48-8

• 114746-70-2

Reference: [1] Tetrahedron, 1999, vol. 55, # 30, p. 9073 - 9088
[2] Tetrahedron Letters, 1985, vol. 26, # 50, p. 6193 - 6196

Downstream Synthesis Route 2

• 15186-48-8

• 23788-74-1

Reference: [1] Journal of Medicinal Chemistry, 1984, vol. 27, # 9, p. 1142 - 1149
[2] Chemical & Pharmaceutical Bulletin, 1981, vol. 29, # 12, p. 3593 - 3600

Downstream Synthesis Route 3

• 15186-48-8

• 83400-91-3

Reference: [1] Journal of Organic Chemistry USSR (English Translation), 1990, vol. 26, # 11, p. 2070 - 2081[2] Zhurnal Organicheskoi Khimii, 1990, vol. 26, # 11, p. 2398 - 2411

Downstream Synthesis Route 4

• 558-13-4
• 15186-48-8

• 56017-84-6

Reference: [1]Yadav, Ram N.; Paniagua, Armando; Banik, Bimal K.
[Journal of the Indian Chemical Society, 2021, vol. 98, # 4]

* For details of the synthesis route, please refer to the original source to ensure accuracy.