WUN40378

• CAS: 2328140-37-8
• Catalog Number: ACM2328140378
• Category: Inhibitors
• Molecular Weight: 243.24
• Molecular Formula: C13H10FN3O
• Description: WUN40378 is compound first reported in PCT Int. Appl. (2019), WO 201909959, in which it was described as CBFβ-​RUNX1 inhibitor. WUN40378 is very similar to Ro 5-3335 but with an F instead of Cl. WUN40378 is also analog of Ro 24-7429.
• Synonyms: WUN40378; WUN 40378; WUN-40378; Ro5-3335 analog; Ro 5-3335 analog; Ro 5-3335 analog; Ro 24-7429 analog; Ro 24-7429 analog; Ro24-7429 analog
• IUPAC Name: 7-fluro-1,3-dihydro-5-(1H-pyrrol-2yl)-2H-1,4-benzodiazepin-2-one
• Canonical SMILES: O=C1NC2=CC=C(F)C=C2C(C3=CC=CN3)=NC1
• InChI: InChI=1S/C13H10FN3O/c14-8-3-4-10-9(6-8)13(11-2-1-5-15-11)16-7-12(18)17-10/h1-6,15H,7H2,(H,17,18)
• InChI Key: WRPBNGDPQRHZHC-UHFFFAOYSA-N
• Solubility: To be determined
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 139339-45-0; 2328140-37-8; 30195-30-3
• Biological Target: WUN40378 is compound first reported in PCT Int. Appl. (2019), WO 201909959, in which it was described as CBFβ-RUNX1 inhibitor.
• Drug Formulation: to be determined
• Elemental Analysis: C, 64.19; H, 4.14; F, 7.81; N, 17.28; O, 6.58
• Exact Mass: 243.0808
• HS Tariff Code: 2934.99.9001
• In Vitro Activity: TBD
• In Vivo Activity: TBD
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).