SRI-37330 free base

• CAS: 2322245-42-9
• Catalog Number: ACM2322245429
• Category: Inhibitors
• Molecular Weight: 388.41
• Molecular Formula: C16H19F3N4O2S
• Description: SRI-37330 is a novel inhibitor of TXNIP expression, decreasing glucagon secretion and action and blocking hepatic glucose output, reversing obesity- and STZ-induced diabetes and hepatic steatosis.
• Synonyms: SRI-37330 free base; SRI37330 free base, SRI 37330 free base
• IUPAC Name: N-((1-(6-(trifluoromethyl)quinazolin-4-yl)piperidin-3-yl)methyl)methanesulfonamide
• Canonical SMILES: CS(=O)(NCC1CN(C2=C3C=C(C(F)(F)F)C=CC3=NC=N2)CCC1)=O
• InChI: InChI=1S/C16H19F3N4O2S/c1-26(24,25)22-8-11-3-2-6-23(9-11)15-13-7-12(16(17,18)19)4-5-14(13)20-10-21-15/h4-5,7,10-11,22H,2-3,6,8-9H2,1H3
• InChI Key: WRSNFEVXRKOMLL-UHFFFAOYSA-N
• Solubility: To be determined
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 2322245-49-6 (HCl); 2322245-42-9 (free base)
• Drug Formulation: To be determined
• Elemental Analysis: C, 49.48; H, 4.93; F, 14.67; N, 14.42; O, 8.24; S, 8.25
• Exact Mass: 388.118
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).