WCK-5153

• CAS: 1436862-38-2
• Catalog Number: ACM1436862382
• Category: Inhibitors
• Molecular Weight: 377.37
• Molecular Formula: C12H19N5O7S
• Description: WCK-5153 is a Novel Inhibitor of PBP2 Showing Potent "β-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones. WCK 5153 demonstrated specific high-affinity binding to PBP2 of A. baumannii. WCK 5153 shows a potent β-lactam enhancer effect against A. baumannii, including a multidrug-resistant OXA-23-producing ST2 international clone.
• Synonyms: WCK-5153; WCK 5153; WCK5153
• IUPAC Name: (2S,5R)-7-oxo-2-(2-((S)-pyrrolidine-3-carbonyl)hydrazine-1-carbonyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate
• Canonical SMILES: O=C(NNC([C@H]1N(C[C@H]2CC1)C(N2OS(=O)(O)=O)=O)=O)[C@H]3CCNC3
• InChI: InChI=1S/C12H19N5O7S/c18-10(7-3-4-13-5-7)14-15-11(19)9-2-1-8-6-16(9)12(20)17(8)24-25(21,22)23/h7-9,13H,1-6H2,(H,14,18)(H,15,19)(H,21,22,23)/t7-,8+,9-/m0/s1
• InChI Key: NAURQUDBIPQVFZ-YIZRAAEISA-N
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 38.19; H, 5.08; N, 18.56; O, 29.68; S, 8.50
• Exact Mass: 377.1005
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).